A randomized clinical trial ends with a non-significant finding: treatment and c

Question

A randomized clinical trial ends with a non-significant finding: treatment and control are not significantly different. However, the investigators notice that there is a significant treatment effect among participants who were smokers (i.e., subjects who, at baseline, reported smoking at least 5 cigarettes / day). Give one argument against pursuing this finding by conducting a new trial limited to people who smoke at least 5 cigarettes / day. Give one argument in favor of pursuing it.

CoursesNathan Bunkowske (sec 320) Summer 2018 moodle 3.2 29 Assignment 6 (Due 7/31) Completion of these questions will demonstrate to you the importance of pre-testing forms Improving a concomitant medications CRF: Consider this draft case report form for a large influenza treatment study. At first glanoe, it appears clear and well organized. You are study staff and are illing out this form during a participants baseline visit Part A. Answer either 1 or 2 (not both). 1 Suppose this participant is in the last week of a three-week course of antibiotics for an ear infection (that is, one week tollowing this visit will be the last day of taking the antiblotic). How would you filt out one of the medication rows for this participant? (There is no one correct answer ) 2. Suppose the next participant uses an inhaled bronchodilator on an as-needed basis for asthma, and has done so since childhood. How would you fill out one of the medication rows for this parte pent? There is no one cored answer.) Part B. Considering your answer above, describe one improvement you would make to the form

Explanation / Answer

Smoking is one of the major issue.The study is little hypothetical.

But there is a significant decrease in the number of cigarettes smoked by the smoker after treatment .It means the treatment is effective.Which is a positive finding in this clinical trial and favouring it.

However at the same time people even after treatment smoke the same number of cigarettes per day.It means the patient has not improved in the clinical trail which indicates negativity and goes against it.

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