What are the two main differences between capillaries in the periphery and capil

Question

What are the two main differences between capillaries in the periphery and capillaries surrounding the brain?

A. Capillaries surrounding the brain have no pores and are not surrounded by membranes of astrocyte cells.
B. Capillaries surrounding the brain have pores and are not surrounded by membranes of astrocyte cells.
C. Capillaries surrounding the brain have pores and are surrounded by membranes of astrocyte cells.
D. Capillaries surrounding the brain have no pores and are surrounded by membranes of astrocyte cells.

Explanation / Answer

The answer is option D

Astrocytic foot processes surround brain capillaries induce endothelial cells to form tight junctions.

These endothelial tight junctions are the basis of blood-brain-barrier, which maintains homeostasis in the CNS.

Loss of the integrity of the endothelial barrier causes fluid to leak into the interstitial space,results in fatal conditions

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