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In a trial of 275 patients who received 10-mg doses of a drug daily, 33 reported

ID: 3127735 • Letter: I

Question

In a trial of 275 patients who received 10-mg doses of a drug daily, 33 reported headache as a side effect. Use the information to complete (a) through (d) below. Obtain a point estimate for the population proportion of patients who received 10-mg doses of a drug daily and reported headache asa a side effect. p(hat)= (B) Verify that the requirments for constructing a confidence interval about p are satisfied. Are the requirements for constructing a confidence satisfied? (C) Construct a 99% confidence interval for the population proportion of patients who receive the drug and report headaches as a side effect. The 99% confidence interval is (_,_) (D) Interpret the confidence interval. Which statement below best interprets the interval -We are 99% confident that the interval does not contain the true value of p. -There is 99% chance that the true value of p will not fail in the interval. -We are 99% confident that the interval contains the true value of p.

Explanation / Answer

a)

Note that              
              
p^ = point estimate of the population proportion = x / n = 33/275 =   0.12   [ANSWER]

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b)

As this is a random sample, and

n p^ (1-p^) = 29.04 < 5,

then the requirement is satisfied.

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c)

      
              
Also, we get the standard error of p, sp:              
              
sp = sqrt[p^ (1 - p^) / n] =    0.019595918          
              
Now, for the critical z,              
alpha/2 =   0.005          
Thus, z(alpha/2) =    2.575829304          
Thus,              
Margin of error = z(alpha/2)*sp =    0.05047574          
lower bound = p^ - z(alpha/2) * sp =   0.06952426          
upper bound = p^ + z(alpha/2) * sp =    0.17047574          
              
Thus, the confidence interval is              
              
(   0.06952426   ,   0.17047574   ) [ANSWER]

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d)

We are 99% confident that the interval contains the true value of p. [ANSWER, C]

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