Development of an effective vaccine against HIV has proven difficult. Even thoug
ID: 3150593 • Letter: D
Question
Development of an effective vaccine against HIV has proven difficult. Even though the immune systems of infected individuals produces antibodies that neautralize circulating viris, the disease destroys the CD4 T cells producing those antibodies. Balaz et al. (2011) investigated a novel HIV treatment that bypasses the immune system. They used a special strain of :humanized" mice that carry human CD4 T cells, which are susceptible to HIV. treatment mice recievd human antibody-producing genes, which wer injected into leg muscle using a marmless virus. Control mice were injected with a reporter gene instead (luciferase). all mice were then injected with high doses of HIV. the data below record the percentage of healthy CD4 T cells remaining in the mice five weeks later. a High value indicates that many CD4 T cells remain, and hence that HIV has been neautralized, whearas a low value indicates that the mouse has succumbed to the disease.
Antibody treatment mice: 94, 96, 92, 88, 84, 81, 76, 54
Control teatment mice: 20, 15, 11, 7, 3, 0
B) what are the most-plausible values for the means of each of the two treatments?
Explanation / Answer
B) what are the most-plausible values for the means of each of the two treatments?
It is their sample means.
For ANTIBODY TREATMENT:
Getting the mean, X,
X = Sum(x) / n
Summing the items, Sum(x) = 665
As n = 8
Thus,
X = 83.125 [ANSWER]
For the CONTROL TREATMENT:
Getting the mean, X,
X = Sum(x) / n
Summing the items, Sum(x) = 56
As n = 6
Thus,
X = 9.333333333 [ANSWER]
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