A 7 year old female with a history of previous UTI’s suddenly develops painful,

Question

A 7 year old female with a history of previous UTI’s suddenly develops painful, dark-orange colored urine, with fever and back pain. Her urinalysis reveals dipstick tests that are positive for protein (2+), blood (1+), leukocyte esterase (4+), and nitrate (4+). The microscopic examination yields 20-25 WBC/HPF, 5-10 RBC/HPF, 5-10 WBC Casts/LPF, and numerous bacteria. The patient has been taking Tylenol and vitamin C supplements daily for the past 24 hours, since the condition began.

Based on the results 1) what diagnosis/condition would you surmise at this point? 2) what dipstick/microscopic test support this? 3) is the patient’s history significant? 4) can the medication or vitamin supplement have any impact on the test results?

Explanation / Answer

Women often experience urinary tract infections that are often marked by pain in the abdomen or lower back. The urine is dark-orange colored due to blood mixing with dark yellow urine. The infection may be due to bacteria E. coli, (MayoClinic).

Leukocyte esterase test dipstick that indicates; the presence of white blood cells either as whole cells or as lysed cells; supports this assumption and the microscopic examination yielding 20-25 WBC/HPF also backs this assumption.

Yes with all the medical history and the details of the tests done; one can proceed with the treatment.

Yes according to researches; Vitamin C spiking of urine has shown to demonstrate false-negative results at various concentrations, (Ko DH, 2015) in case of Dipstick Test Results.

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