Researchers grafted human cancerous cells onto 20 healthy adult mice and then ra

Question

Researchers grafted human cancerous cells onto 20 healthy adult mice and then randomly assigned 10 of these mice to be treated with tumor-specific antibodies. They found that only 1 of the 10 mice treated with antibodies developed metastases, whereas all 10 of the 10 mice in the control group developed metastases.

We want to compare the proportions of mice developing metastases under the two conditions. Here, a hypothesis test is

      a. not appropriate because the respective counts of successes and failures are not large enough.

      b. not appropriate because the experiment is not double-blind.

      c. appropriate because a total of 20 mice is large enough for any inference.

      d. appropriate because the study was randomized.

Explanation / Answer

Answer: d appropriate because the study was randomized.

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