Using the sensitivity and specificity measures you calculated in Question 2 abov

Question

Using the sensitivity and specificity measures you calculated in Question 2 above, calculate what the PPV would be if you screen the total population of Epiville where you estimate the prevalence of SS to be only 1%. (hint: draw a new 2x2 table and write the new column totals for the Clinician Gold Standard using the new "true" population prevalence of 1%, given a total N=1000 Then use the specificity = .96 and sensitivity = .90 to fill in the rest of the 2x2 table.) NOTE: ONLY USE THE SENSITIVITY AND SPECIFICITY VALUES ROUNDED TO 2 DECIMAL PLACES THAT APPEAR IN THE ANSWER TO QUESTION 2.

Explanation / Answer

The table is as follows :

As can be seen from above

SS total positive = 1% of 1000 = 10.

sensitivity = 9/10 =0.9

GS negative SS positive = 990*0.96 = 950

So PPV = 9/49 = 0.18

SS Positive Negative Total Positive 9 40 49 GS Negative 1 950 951 Total 10 990 1000

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