It appears that eating oat bran lowers cholesterol slightly. At a time when oat
ID: 3153930 • Letter: I
Question
It appears that eating oat bran lowers cholesterol slightly. At a time when oat bran was something of a fad, a paper in the New England Journal of Medicine found that it had no significant effect on cholesterol. The paper reported a study with just 20 subjects. Letters to the journal denounced publication of a negative finding from a study with very low power.
Explain why lack of significance in a study with low power gives no reason to accept the null hypothesis that oat bran has no effect.
Explanation / Answer
OPTION C: Because low power means that there is a high probability that the null hypothesis will not be rejected although the alternative hypothesis is true. [ANSWER]
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Note that a low power means a high probability of a type II error, that is, incorrectly failing to reject a false null hypothesis.
[Power = 1 - P(Type II)]
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