d. Tubuloacinar gland e. Simple gland otolaryngologist. A bronchial biopsy indic
ID: 3165013 • Letter: D
Question
d. Tubuloacinar gland e. Simple gland otolaryngologist. A bronchial biopsy indicates altered structures in the epithelial cells. Which of the following, if altered to reduce function, is most likely involved in this patient's condition? 8. With a S-year history of chronic respiratory infections, a 23-year-old, non-smoking man is referred to an a Hemidesmosomes b. Cilia c. Basolateral cell membrane folds d. Microvilli e. Tight junctions ld girl is referred to a pediatric gastroenterology clinic due to a history of generalized weakness, slow growth, and refractory diarrhea. For the past month she has been hospitalized regularly to receive parenteral nutrition. Examination of the absorb epithelium lining her small intestine confirms that the failure to nutrients is most likely due to a significant decrease in which of the following? a. Microvilio b. Gap junctions - a. Microvilli d. Cell layers eBasement membrane thickness 10. A 42-year-old woman of Mediterranean descent presents with multiple oral blisters and a few cutaneous blisters on her back and buttocks. The superficial bullae are fragile, some have unroofed to form ulcerated lesions, and there is a positive Nikolsky sign. Blood tests reveal antibodies to a subfamily of cadherins and immunohistochemical staining of a biopsy from the oral mucosa shows distribution of the antigen throughout the epithelium. In what structures is the defect that is causing this patient's condition? b. Tight junctions e. Hemidesmosomes d. Gap junctions e. Reticular lamina I1. Which of the following connective tissue components is located in the ECM but not in the ground substance? a. Collagen bundles b. Fibronectin c. GAGs d. Hyaluronan ycans 12. What cells numerous in loose connective tissue are filled with secretory granules and stain with metachromasia? a. Macrophages b. Mast cells c. Fibrocytes d. Active fibroblasts e. Leukocytes 13. What is the first step of collagen production that occurs after the protein undergoes exocytosis? a. Cross-linking of collagen fibrils with a short linking collagen b. Removal of the terminal non-helical domains by peptidases Hydroxylation of lysine and proline e. Disulfide bond formation 14. What is an important part of the role played by macrophages during maintenance and renewal of strong c. - d. Assembly of subunits to form a larger structure extracellular fibers in connective tissue?Explanation / Answer
8.
a. Ciliary function of epithilial cells is if altered induces increased infiltration of pathogen and subsequently leads to chronic infection.
9.
a. Microvilli are responsible for absorption of nutrient in intestine and hence if its function is reduced leads to weakness due to lack of nutrients.
10.
a. Defect in Desmosomes function leads to formation of blisters caused by pemphigus vulgaris.
11.
a. Ground substance constitutes most of the components of extracellular matrix except fibrous materials such as collagen and elastin. Hence option is A.
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