Hospital A treats nasal tumors in dogs with Protocol A: 19 fractions 3 Gy/fracti

Question

Hospital A treats nasal tumors in dogs with Protocol A: 19 fractions 3 Gy/fraction Delivered daily, Monday through Friday over 25 days Total dose = 57 Gy

Hospital B treats nasal tumors in dogs with Protocol C: 19 fractions 3 Gy/fraction Delivered Monday, Wednesday, Friday (every other day) over 40 days Total dose = 57 Gy

Field size, isodose distributions, equipment, treatment planning and distribution of tumors are the same for both groups.

Discuss the difference you would expect in each group (Protocol A vs. Protocol C) for:

A. Acutely responding normal tissues

B. Late responding normal tissues

C. Tumor and potential impact on tumor control

Explanation / Answer

A. acutely responding noral tissues:due to fequent repeated dosages in protocol A there will be immediate visual affects on normal tissue.
?B. due to long term radiation doses in protocol C patients may get suffered late responding normal tissues.
?C.tumor and potential impact on tumor control can be affected by both protocols with different affinities in different cases, but acutal effect can only be tell when the type of tumor we are talking about is taken into consideration.
?both these protocols have there pros and cons.

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