QUESTION 4 Which is false regarding the functionality of barbiturates? They have

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QUESTION 4 Which is false regarding the functionality of barbiturates? They have a stronger effect than benzodiazepines They are extremely dangerous when combined with other CNS depressants They enhance GABAergic signaling by allowing low levels of GABA to bind more efficiently to ion channels They are useful for epilepsy contro QUESTION 5 What neurotransmitter do drugs of abuse all modify? Glutamate GABA Serotonin Dopamine QUESTION 6 Which of the following is a molecular mechanism of tolerance? Increasing numbers of receptors inhibited by a drug ceaing numbers of receptors activated by a drug Metabolic changes that result in breaking down a drug more slowly All of the above A and B

Explanation / Answer

Answer to question 4:

The correct option will be "They enhance Gabaergic signaling by allowing low level of GABA to bind more effectively to ion channels."

Explanation: barbiturates potentiate GABA by decreasing the rate of its dissociation, and increasing duration of GABA activated ion channels opening.

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