I was thinking that the answer is a. exonuclease. I know that Pol I has an exonu

Question

I was thinking that the answer is a. exonuclease. I know that Pol I has an exonuclease that degrades DNA and since the graph shows the line that decreases in % label remaining over time, I thought it might be A. I was just wondering if that answer is right or if I'm on the right track? Thank you!

Exonuclease vs. Endonuclease DNA strand w/uniformly abeelkod nucleotides 5 80 4 60 3 40 DNA strand 20 5 10 20 25 30Tabeled INCUBATION TIME minutes nucleotides The enzyme added at t-0 is an: A. Exonuclease B.E Explain

Explanation / Answer

Ans : A

Since you see an immediate decrease in the percentage of terminally labeled nucleotide, means the terminal degradation is very fast. Whereas percentage of uniformly labeled nucleotide is gradually decreasing confirms that terminal degradation is in process. Its signature of exonuclease.

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