The transcription factor Dsx (doublesex) is alternatively spliced by binding of

Question

The transcription factor Dsx (doublesex) is alternatively spliced by binding of the Tra transformer) protein, such as there are genes associated speaitic isofoms. The male isoform of Dsx actvates male traits and suppresses female traits What phenotypes would you expect in fies that are homozygous for a mutation in Dsx thar disrupts the Tra binding she? Tra protein encourages splice site use Dsx-F Results of dsx splicing when tra is absent ( O A XX phenotypically tomale, XY phenotypically male OB xx phenotypically female, XY phenotypically female O C xXx-phenotypically male, XY phenotypically female O D x0x-phenotypically male, XY phenotypically male EXx-phenotypically temale, XY letha

Explanation / Answer

Answer: XX-phenotypically male, XY-phenotypically male.

Mutation in Tra binding site results in the production of unspiliced mRNA which leads to the activation of male specific trait (irrespective of the genotype).

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