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Genetics and Health Tay-Sachs disease is a rare inherited disorder that progress

ID: 3166295 • Letter: G

Question

Genetics and Health

Tay-Sachs disease is a rare inherited disorder that progressively destroys nerve cells (neurons) in the brain and spinal cord. It begins to manifest in infants after 6 months, when they begin to have difficulty with motor skills. The child later may experience seizures, loss of vision, and paralysis.

Explain how two parents who do NOT have the disease can have a child who is afflicted with Tay-Sachs disease.

What are some ways that parents could determine if their children are at risk for inheriting a genetic disease?

Explanation / Answer

1- parents being carrier of rare disease might lead to have affected child as the recessive allele from both the parents can be transfeered to teh child leading to homzygous recessive condition .

2- studying the family history of disease by pedigree analysis amd analysing the homozygosity or heterozygosity of parents before they have the child to know the rsik ratio.

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