The biosynthetic pathway that generates pyridoxal phosphate (PLP) is shown below

Question

The biosynthetic pathway that generates pyridoxal phosphate (PLP) is shown below ? ?? ATP FAD Biotin OPO32 NAD+ Acetyl CoA OH NADH Step 1 O OH Step 2 Step 3 ? ?? OPO32 OPO32 ?? NH3 glutamate a-ketoglutarate Step 4 O OH Step 5 Step 6 OPO32 ???? ?? ?? Using the list of cofactors in the box above, fill in which cofactor, if2 any, is required for each of the indicated steps in the pathway. Note hat all co-substrates have been provided in this schematic, and no tep requires more than one cofactor ?? 203PO +2 H20 Pi Na Me Step Cofactor Step 7 3 2-03PO N Me 5 PLP

Explanation / Answer

ANSWER

In step 6, phosphate will be provided by ATP.

Options with dash don’t need any cofactor for the conversion

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