1) Which of the following are cis-acting sequences? A). promoters B). Enhancers
ID: 3167197 • Letter: 1
Question
1) Which of the following are cis-acting sequences?
A). promoters
B). Enhancers
C ). Repressors
D). Two of the above
E). All of the above.
2). When a transcription factor which functions as an activator binds an enhancer sequence, which of the following types of enzymes is it likely to recruit in order to activate transcription?
A). Histone acetyltransferases
B). Histone demethylases
C). Histone methyltransferases
D). Histone demethylases
E ). Two of the above
F). All of the above
3). Formation of double - stranded RNAs inside of the cell activates the RNA interference mechanisms involving the enzyme complexes DICER and RISC, leading to the destruction or inactivation of target mRNAs. How is RISC, guided to the mRNA that is to be destroyed or inactivated?
A ). There is a RNA - binding protein in RISC which recognize the consensus sequence in the target mRNA.
B). RISC includes ribosomal proteins and RNAs which bind to The Shine - Delgarno sequence of the mRNAs.
C ). The strand of the double - stranded RNAs that is complementary to the sequences of specific target mRNAs serves as the " guide ".
D ). Two of the above
E ). All of the above
4 ) You are testing a drug which blocks the activity of histone acetyltransferases in eukaryotic cell. In general what do you expect to observe with regards to the chromatin and gene expression in treated cells?
A ). The chromatin near cis-regulatory sequence will be more open and less gene transcription would occur.
B). The chromatin near cis -regulatory sequences will be more open and more gene transcription would occur.
C ). The chromatin near cis -regulatory sequences will be more closed and less gene transcription would occur.
D ). The chromatin near cis-regulatory sequences will be more closed and more gene transcription would occur.
E ). There would be no effect on chromatin or gene transcription. HATs are involved in regulating the assembly of histones.
Explanation / Answer
1-- promoter and enhancer as
repressor is trans acting..so the answer is D(TWO OF THE ABOVE)
2--Histone acetyltransferases and histone demethylases..option E(TWO OF THE ABOVE)
3--A and C so the answer is option D(Two of the above)
4-- answer is optn B as it is asking only about chromatin and gene expression it will be more open and more gene transcription would occur..
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