(3 pts) Genotypic Frequencies Envision a gene with just 2 alleles, A & B. If the

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(3 pts) Genotypic Frequencies Envision a gene with just 2 alleles, A & B. If the allelic frequencies are A-0.8 and B -0.2, what are the frequencies for all of the possible genotypes in the population? (List each genotype and its expected frequency). (3 pts) Use the table below. What is the probability of a Caucasian American having both of these genotypes? Show your work. Note- if you are understanding this question, you will only provide one number for it-anything else is incorrect. 1.1, 2 for DQa and B, B for LDLR? Genetic Marker Allele U.S. Caucasian HLA DQAI LDLR 1.2 4.2/4.3 1.1 0.158 0.1900.0730.145 0.192 0.214. 0.028 0.448 0.552 1.3 4.1 Multiple Choice, 2 pts. each; select the best answer You are analyzing the alleles present in a particular person for a well known tetranucleotide repeat. You find an allele that has not been observed before. It is located between allele 11 and allele 12 and clearly closer to allele 12. What would you call it? d. 11+ For a given loci, the frequency of allele A and allele B a heterozygous individuals expected in the population? 0.8 and O 2, respectively what is the % of a. 24% b. 16% ?. 32% d. 50% When 9 alleles are present in a population, genotypes are present a. 18 b. 27 c. 36 d. 45

Explanation / Answer

(3)

Frequency of A=0.8 and B=0.2

Possible genotype sin the population with Hardy weinberg equilibrium

AA, AB, BB

AA=p^2= 0.8 x 0.8=0.64 =64%

BB=q^2=0.2 x 0.2=0.04=4%

AB=2pq=2x 0.8 x0.2=0.32=32%

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