5. Using the values a = 7.241 and b = 0.176 with the novel formula in Figure 2 ,

Question

5. Using the values a = 7.241 and b = 0.176 with the novel formula in Figure 2 , what is the predicted weight in kilograms for a child 3 years of age? Show your calculations.

6. Using the values a = 7.241 and b = 0.176 with the novel formula in Figure 2 , what is the predicted weight in kilograms for a child 5 years of age? Show your calculations.

7. In Figure 3 , some of the actual mean weights represented by blue line with squares are above the dotted straight line for the novel formula, but others are below the straight line. Is this an expected nding? Provide a rationale for your answer.

Introduction Medications and other therapies often necessitate knowing a patient's weight. However a child may be admitted to a pediatric intensive care unit (PICU) without a known weight and instability and on-going resuscitation may prevent obtaining this needed weight Clinicians would benefit from a tool that could accurately estimate a patient's weight when such information is unavailable. Thus Flannigan et al. (2014) conducted a retro- spective observational study for the purpose of determining "if the revised APLS UK Advanced Paediatric Life Support United Kingdom) formulae for estimating weight are appropriate for use in the paediatric care population in the United Kingdom" (Flannigan et al., 2014, p. 927). The sample included 10,081 children (5,622 males and 4,459 females) who ranged from term-corrected age to 15 years of age, admitted to the PICU during a 5-year period. Because this was a retrospective study, no geographic location, race, and ethnicity data were collected for the sample. A paired samples t-test was used to compare mean sample weights with the APLS UK formula weight. The "APLS UK formula weight F (0.05 x age in months) 4' significantly overestimates the mean weight of children under 1 year admitted to PICU by between 10% and 25.4%" (Flannigan et al, 2014, p 928). Therefore, the researchers concluded that the APLS UK formulas were not appropri- ate for estimating the weight of children admitted to the PICU Relevant Study Results Simple linear regression was used to produce novel formulae for the prediction of the mean weight specifically for the PICU population" (Flannigan et al., 2014, p. 927). The three novel formulas are presented in Figures 1, 2, and 3, respectively. The new formulas calculations are more complex than the APLS UK formulas. "Although a good estimate of mean weight can be obtained by our newly derived formula, reliance on mean weight alone will still result in significant error as the weights of children admitted to PICU in each age and sex gender group have a large standard deviation...Therefore as soon as possible after admission a weight should be obtained, e.g., using a weight be (Flannigan et al., 2014, p. 929)

Explanation / Answer

(5) here a=7.241 and b=0.176 , so we use the age in months

here age x==3 years=3*12=36 months

weight=a+b*x=7.241+0.176*36=13.577

(6) here a=7.241 and b=0.176 , so we use the age in months

here age x=5 years=6*12=60 months

weight=a+b*x=7.241+0.176*60=17.801

(7) it means that the age in year is not good for predicting weith as compared to months,

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