You read a report suggesting that E. coli expresses a protein repressor of the l

Question

You read a report suggesting that E. coli expresses a protein repressor of the lactasegene. The repressor binds directly to the DNA and could be responsible for the absence of lactasemRNA. A recent report contains the DNA base sequence the repressor binds. Given thisinformation, name the specific feature on the B-form of DNA where would you expect the proteinregulator to bind.

3. (1 point) You read a report suggesting that E. coli expresses a protein repressor of the lactase gene. The repressor binds directly to the DNA and could be responsible for the absence of lactase mRNA. A recent report contains the DNA base sequence the repressor binds. Given this information, name the specific feature on the B-form of DNA where would you expect the protein regulator to bind.

Explanation / Answer

Since it is a prokaryote(ecoli) so there are no distal and proximal promoter elements .... so it has a simple prokaryotic promoter with closeness to TATA consensus .... now the repressor is bound to DNA and inactivates mRNA transcription..... so it means it work like the lac-repressor works inlac operon as (repressor without lactose) is bound to promoter sequence the RNApolymerase cannot bind ... so most possibly the repressor either binds directly at the promoter or the repressor and promoter binding sites do share some overlapping sequence such that wher repressor is bound RNAPolymerase cannot bind and vice versa

Hope that answers feel free to discuss if u wanted to tell something else ... i will be glad to reply you happily

Regards .... and i must tell it was a great quesion ....

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