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A 7-year cohort study involving 1500 Australian adolescents assessed the associa

ID: 3219190 • Letter: A

Question

A 7-year cohort study involving 1500 Australian adolescents assessed the association between frequency of cannabis use and subsequent depression in young adulthood. From the results of the study, shown in the following table, calculate whether a relationship exists between adolescent cannabis use and subsequent depression. Please interpret the result.

Cannabis Use

Number

%

Number of Depression Cases

Person-Years at Risk

None to < 5 times ever

1,108

73.9

25

7,352

5 times ever to less than weekly

236

15.7

9

1,430

1 to 4 times per week

86

5.7

4

472

Daily

70

4.7

3

315

Total

1,500

100.

41

9,569

Cannabis Use

Number

%

Number of Depression Cases

Person-Years at Risk

None to < 5 times ever

1,108

73.9

25

7,352

5 times ever to less than weekly

236

15.7

9

1,430

1 to 4 times per week

86

5.7

4

472

Daily

70

4.7

3

315

Total

1,500

100.

41

9,569

Explanation / Answer

First we calculate incidence rate for all cannabis use

Incidence rate is calculated at per 1000 person year

It can be interpreted as the number of depression cases decreases accordingly to the Cannabis use. The cannabis seems to decrease the rate incidence of depression in user

Cannabis Use Number % Number of Depression Cases Person-Years at Risk Incidence rate Relative risks None to < 5 times ever 1,108 73.9 25 7,352 3.400435256 5 times ever to less than weekly 236 15.7 9 1,430 6.293706294 1.850853147 1 to 4 times per week 86 5.7 4 472 8.474576271 2.49220339 Daily 70 4.7 3 315 9.523809524 2.800761905 Total 1,500 100 41 9,569 4.284669244
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