Which of the following statements about pyruvate is most accurate? Pyruvate can

Question

Which of the following statements about pyruvate is most accurate? Pyruvate can be produced only from carbohydrates; Pyruvate dehydrogenase complex does not belong to the Krebs cycle. Therefore, pyruvate dehydrogenase is not a step-controlling enzyme for the Krebs cycle; Pyruvate can be reversibly converted to phosphoenolpyruvate by pyruvate kinase; Pyruvate is a main precursor of oxaloacetate in the Krebs cycle; Pyruvate dehydrogenase converts pyruvate to acetyl CoA and generates one NADH that is equivalent to 2ATP if the NADH is transferred to mitochondria via glycerol 3-phosphate shuttle system.

Explanation / Answer

Correct answer is B

Pyruvate dehydrogenase complex does not belong to Krebs Cycle.Therefore pyruvate dehydrogenase is not a step controlling enzyme for krebs cycle.

PDH complex catalyses the conversion of Pyruvate into Acetyl CoA. Acetyl CoA then enters Krebs cycle and forms oxaloacetate. Therefore action of PDH comples does not determine the control of krebs cycle,.

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