Payne, B. A. et al. (2013) present evidence that a low level of heteroplasmic mt
ID: 323010 • Letter: P
Question
Payne, B. A. et al. (2013) present evidence that a low level of heteroplasmic mtDNA exists in all tested healthy individuals.
What genetic conditions within a given mitochondrion are likely to contribute to such a variable pool of mitochondria?
The most likely genetic condition within a given mitochondrion would be some sort of mutagenic agents such as reactive oxygen species.
The most likely genetic condition within a given mitochondrion would be some sort of mutator gene such as a faulty polymerase.
The most likely genetic condition within a given mitochondrion would be some sort of mutagenic factors such as mistakes in cell division.
The most likely genetic condition within a given mitochondrion would be some sort of mutagenic factors such as mistakes of reparation system.
Explanation / Answer
The most likely genetic condition within a given mitochondrion would be some sort of mutagenic factors such as mistakes of reparation system.
Presence of more than one type of organellar genome (mitochondrial DNA or plastid DNA) within a cell or individual is called heteroplasmy. It could lead to a less efficient oxidative phosphorylation hence leads to mistake in respiratory process.
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