In May 1993, an outbreak of Hantavirus Pulmonary Syndrome (HPS) occurred in the
ID: 3235519 • Letter: I
Question
In May 1993, an outbreak of Hantavirus Pulmonary Syndrome (HPS) occurred in the Southwestern United States. A study was performed to determine risk factors for HPS. 17 patients with HPS were compared with 93 household controls. Interviews of all participants were performed during June and July of 1993 to obtain information about activities that may have been associated with HPS. One of these activities was hand plowing the ground. Of 17 HPS patients, 5 recalled hand plowing the ground. Of 93 controls, 4 recalled hand plowing.
a) (2 pts) What type of study is this?
b. (2 pts) Construct a 2 X 2 table for these data.
c. (4 pts) Calculate the appropriate measure of association between hand plowing and HPS in this study population and state what it means.
Explanation / Answer
Answer:
In May 1993, an outbreak of Hantavirus Pulmonary Syndrome (HPS) occurred in the Southwestern United States. A study was performed to determine risk factors for HPS. 17 patients with HPS were compared with 93 household controls. Interviews of all participants were performed during June and July of 1993 to obtain information about activities that may have been associated with HPS. One of these activities was hand plowing the ground. Of 17 HPS patients, 5 recalled hand plowing the ground. Of 93 controls, 4 recalled hand plowing.
Case control study
b. (2 pts) Construct a 2 X 2 table for these data.
HPS
Control
Total
Hand plow
5
4
9
No hand plow
12
89
101
Total
17
93
110
c. (4 pts) Calculate the appropriate measure of association between hand plowing and HPS in this study population and state what it means.
Odds ratio = (5*89)/(12*4) =9.27
The persons who had HPS hand plowed 9.27 times more often than persons who did not have HPS.
HPS
Control
Total
Hand plow
5
4
9
No hand plow
12
89
101
Total
17
93
110
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