Which of the following statements about even & odd-chain fatty acids is/are fals

Question

Which of the following statements about even & odd-chain fatty acids is/are false? (There is more than one answer)

A) A difference between even-chain and odd-chain fatty acids is that only odd-chain fatty acids produce propionyl groups bound to CoA

B) Humans have all the appropriate enzymes necessary to use even-chain fatty acids as glucogenic precursors through their conversion to propionyl-CoA

C) The products of the oxidation of an odd-numbered fatty acid chain are multiple 3-carbon propionyl groups bound to CoA

D) The product of the oxidation of even-numbered fatty acid chains is multiple acetyl groups bound to CoA molecules.

E) The products of the oxidation of an odd-numbered fatty acid chain are acetyl groups and a final propionyl group attached to CoA

Explanation / Answer

Answer: C and D are False

Odd chain fatty acids are oxidized in the same way as even chain fatty acids up until the formation of Propanyl CoA. In the Last round of beta oxidation of even number fatty acid produce two acetyl Co A whereas odd number fatty acids synthesize one Acetyl CoA and one Propanyl Co A. This propanyl CoA is converted in to succinyl CoA which then enters in to the citric acid cycle.

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