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27) Two drugs A and B, used to the treatment of glaucoma, were tested for effect

ID: 3242879 • Letter: 2

Question

27) Two drugs A and B, used to the treatment of glaucoma, were tested for effectiveness on 10 diseased dogs. Drug A was administered to one randomly chosen eye of each dog and drug B to the other eye. Pressure measurements (the smaller the measurement, the less serious the eye disease) were taken 1 hour later on both eyeballs of each dog Which of the following statements are true? D This is an example of a matched pairs design. There are two factors in this experiment. III) There is no replication in this experiment A) Only I is B) Only II is true C) Only III is true D) I and II are true E) I and III are true

Explanation / Answer

as same dogs are used for drug treatment on the pair of eyes , this is a matched pair design , where Drug A is admisistered to 1 eye and drug 2 is administered to the other eye of the dog.

There is only 1 factor here , Drug treatment and no subject (dog) is given the same drug twice , hence only 1 is correct

b)

as we are giving drugs to dogs , there must not be any prior bias in the selection process of the dogs who are given the drugs. also , we must find out a criteria based on which we are able to quantify the effect of the drug on the dogs. hence choice E . Dogs are used as blocks in the experiment

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