A randomized trial is conducted to evaluate the efficacy of a new cholesterol lo

Question

A randomized trial is conducted to evaluate the efficacy of a new cholesterol lowering medication. The primary outcome is incident coronary artery disease. Participants are free of coronary artery disease at the start of the study and randomized to receive either the new medication or a placebo. Participants are followed for a maximum of 10 years for the development or coronary artery disease. The following data are observed. 1. Compute the relative risk of coronary artery disease in patients receiving the new medication as compared to placebo. Relative Risk = 2. Compute the odds ratio of coronary artery disease in patients receiving the new medication as compared to placebo. Odds Ratio =

Explanation / Answer

1. Relative risk ratio:- 56/800/84/800=0.67

2. Here, first calculate Number with no coronary artery disease with cholestrol medication (800-56=744) and with placebo (800-84=716)

Odds ratio:- 56/744/84/716=0.64

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