Consider a highly deleterious mutation that cuts the juvenile survival probabili

Question

Consider a highly deleterious mutation that cuts the juvenile survival probability in half. The frequency is estimated to be about 1 copy per 3,000 wildtype alleles In a country like the United States (population size = 300,000,000), what is the expected number of individuals homozygous for the deleterious allele? If that mutation is recessive, what is the best estimate for the mutation rate from a functional allele to that deleterious one? If that mutation is dominant, what is the best estimate for the mutation rate from a functional allele to that deleterious one?

Explanation / Answer

Solution:-

a) # = 33

b) = 5.56x10^-8

c)   = 1.67x10^-4

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