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1. What would be considered a positive test result in this situation? 2. What is

ID: 3273956 • Letter: 1

Question

1. What would be considered a positive test result in this situation? 2. What is the sensitivity of using a gallop murmur indication for CHF? 3 What is the specificity of using a gallop murmur indication for CHF? 4. What is the probability of a false negative using gallop murmur as an indication for CHF? 5. What is the probability of a false positive using gallop murmur as an indication for CHF? 6. What is the probability that a person exhibiting a gallop murmur has CHF? A recent study to investigate congestive heart failure (CH) enrolled 259 patients. Among other variables collected, the researchers checked if the patient had a Gallop (S3) murmur The researchers are interested to see if the presence of a murmur is an indication of CHF. That is, consider the murmur to be the "test" (presence of the murmur is a positive test, no murmur is a negative test) for the detection of CHF, the "disease". Here is the data Gallop (S3) murmur No gallop murmur CHF No CH 10 31 215

Explanation / Answer

1) positive test result if patent had Gallop (S3) murmur

here a = 10 ,b = 3 , c = 31 ,d = 215

2) sensitivity = (a/(a+c))*100

= 10/(10 + 31) *100 %

= 24.39 %

3) specificity = d/(b+d)*100%

= 215 /(215 + 3) * 100 %

=0.9862385 *100%

=98.62385 %

4)

False Negative = c/(c+d) = 31/(31 + 215) = 0.126016

5)

False Positive = b/(a+b) = 3/13 = 0.23076

6)

probability = 10/(10 +3) = 0.76923