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I need help in these prpblem Part II. Problems 5-7 (80 points total) 5) Cells Af

ID: 3306150 • Letter: I

Question


I need help in these prpblem

Part II. Problems 5-7 (80 points total) 5) Cells Affected by Virus (20 points) consider a rare virus which affects 5 in 1,000,000 GZ07 cells. A western blot test for the virus transfection has been developed that is 80% specificity and sensitivity. phrase used for the probability a cell that gets a negative test result when the virus is not present? (5 points) b) Calculate the number of False Positives given the information above. (10 points) c) To evaluate the conclusion "the Gz07 cell has a lower possibility to be affected by the virus compared to the human cardiac muscle cells", the research team conducts a hypothesis test and obtains a P value that is less than 0.01. It means(circle the correct one below) (5 points) 1) more than 1% probability that this observed difference is due to the random error and the conclusion should be rejected. 1) less than 1% probability that this observed difference is due to the random error and the conclusion is acceptable. 111) more than 1% probability that this observed difference is due to the systematic error and the conclusion should be rejected. IV) less than 1% probability that this observed difference is due to the systematic error and the conclusion is acceptable Page 4 of 7

Explanation / Answer

a) that is called speciifcity

b)as false positive =1-specificity =1-0.8 =0.2

therefore number of false positives =5*p=5*0.2 =1 in 1000000 GZ07 cells

c)

option II is correct

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