Déjà vu and Onward Remember the Abrutze cohort study from HW#4? Below is what yo
ID: 3312777 • Letter: D
Question
Déjà vu and Onward
Remember the Abrutze cohort study from HW#4? Below is what you already know:
A researcher conducted a well-funded, prospective cohort study in 2011, in which she collected data on a total of 450 women who worked at Abrutze Radiology[1] in Houston, TX. After two years of follow-up, the researcher found that 80% of the Abrutze workers had received accidental low doses of radiation. Of the 80% of women who received the accidental low doses, 45% developed an aggressive form of uterine cancer within the two years. Of those women who did not receive the accidental radiation, 25 still went on to develop uterine cancer.
Uterine Cancer
No Uterine Cancer
Total
Radiation
162
198
360
No radiation
25
65
90
Total
187
263
450
IExp = A/(A+B) x 1,000 = 162/360 x 1,000 = .45 x 1,000 = 450 per 1,000
IUnexp = C/(C+D) x 1,000 = 25/90 x 1,000 = .278 x 1,000 = 278 per 1,000
RR = IExp / IUnexp = [A/(A+B)] / [C/(C+D)] = .45/.278 = 1.62 or 1.6
Provide a 1-sentence interpretation of the above finding. .25 point
Uterine Cancer
No Uterine Cancer
Total
Radiation
162
198
360
No radiation
25
65
90
Total
187
263
450
Explanation / Answer
The estimated probability of developing uterine cancer for women with exposure to radiation is 1.62 times higher than the women without any radiation.
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