3. A total of 1600 college students have a rapid strep test (RST) done by a stan

Question

3. A total of 1600 college students have a rapid strep test (RST) done by a standardized culture technique. Of the 1600 students, 1378 have a negative RST and 262 have a positive RST. In addition, a backup throat culture (gold standard) was done on all students. Of the students with a negative RST, 1342 have a negative throat culture. In the group with a positive RST, 179 have a positive throat culture. Fill in the table and calculate the false positive rate (FPR). Disease (Tonsillitis) No disease Positive RST Negative RST (0.5 points) (0.5 points) 0.5 (0.5 points) FPR (1 point)- 4. A total of 36000 patients are enrolled in a randomized control trial to compare the effectiveness of drug X in reducing deaths with a placebo. Out of 21,000 patients in the treatment group, 280 died within 3 years. Out of 15,000 patients in the control group, 480 died within 3 years. Calculate the experimental and control event rate. What is the number needed to treat to prevent 1 death? (3 points)

Explanation / Answer

Q3

FPR = 83/262 = 0.3168

Disease No disease Total Positive RST 179 83 262 Negative RST 36 1342 1378 Total 215 1425

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