a. Is this a des d ex nent or an ervation Applying the Concepts-Advanced study?

Question

a. Is this a des d ex nent or an ervation Applying the Concepts-Advanced study? Expl 10.16 Testing a new pain-relief tablet. Paracetamol is the active ingredient in drugs designed to relieve mild to moderate pain and fever. The properties of paracetamol tablets de- rived from khaya gum were studied in the Tropical Journal of Pharmaceutical Research (June 2003). Three factors be- lieved to affect the properties of parcetamol tablets are (1) the nature of the binding agent, (2) the concentration of the binding agent, and (3) the relative density of the tab- let. In the experiment, binding agent was set at two levels (khaya gum and PVP), binding concentration at two levels t is the experinyéntal unit of the c. What ishe respse variable of thé study? b. Wha s in this x d. Whayáre the tyeatment e. Aft r readin Section 10.3, yoi will learn tha patien periment? representblocking factor i els are i the blocking fact s study. Hoy many I .13 Taste preferences of cockatjels. Applied Anial Beh viour Science Oct. 2000) publihed a study of the taste/prefer- ences of caged cockatie. A sample of birds bred at the (.5% and 4.0%), and relative density at two levels (low and high). One of the dependent variables investigated in the study was tablet dissolution time (i.e., the amount of time, in minutes, for 50% of the tablet to dissolve). The goal of the study was to determine the effect of binding agent, binding concentration, and relative density on mean dissolution time. SECTION 10.2The Completely Randomized Design: Single Factor 511 a. Identify the dependent (response) variable in the b. What are the factors investigated in the study? Give the c. How many treatments are possible in the study? List stu levels of each. them

Explanation / Answer

(a) The dependent variable in the study is the tablet dissolution time or the amount of time taken, measured in minutes, for 50% of a paracetamol tablet to dissolve.

(b) The factors investigated in the study are - binding agent used (levels being khaya gum and PVP), binding concentration (levels being 0.5% and 4.0%) and the relative density of the tablet (levels being low and high).

(c) There are 23 = 8 possible treatments in the study.
The treatments are:
(Khaya gum, 0.5%, low)
(Khaya gum, 0.5%, high)
(Khaya gum, 4.0%, low)
(Khaya gum, 4.0%, high)
(PVP, 0.5%, low)
(PVP, 0.5%, high)
(PVP, 4.0%, low)
(PVP, 4.0%, high).

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