Wilfley and colleagues (2008) tested whether the antiobesity drug sibutramine wo
ID: 3356274 • Letter: W
Question
Wilfley and colleagues (2008) tested whether the antiobesity drug sibutramine would be an effective treatment for people with binge eating disorder. They measured the frequency of binge eating every 2 weeks for 24 weeks during treatment. The following table lists a portion of the data similar to results reported by the authors for the frequency of binge eating over the first 8 weeks of the drug treatment.
(a) Complete the F-table. (Round your answers to two decimal places.)
(b) Use the Bonferroni procedure to make the post hoc test. In which week do we first see significant differences compared to baseline?
Week 2 is the first week where significant differences from baseline are evident.Week 4 is the first week where significant differences from baseline are evident. Week 6 is the first week where significant differences from baseline are evident.Week 8 is the first week where significant differences from baseline are evident.None of the weeks are significantly different from the baseline.
Frequency of Binge Eating Baseline Week 2 Week 4 Week 6 Week 8 4 1 0 0 1 6 4 2 0 0 3 0 1 1 0 1 1 0 1 1 2 2 1 1 1 5 1 2 2 2Explanation / Answer
Answer:
MINITAB used
Wilfley and colleagues (2008) tested whether the antiobesity drug sibutramine would be an effective treatment for people with binge eating disorder. They measured the frequency of binge eating every 2 weeks for 24 weeks during treatment. The following table lists a portion of the data similar to results reported by the authors for the frequency of binge eating over the first 8 weeks of the drug treatment.
Analysis of Variance
Source
DF
Adj SS
Adj MS
F-Value
P-Value
time
4
30.80
7.700
6.31
0.002
subject
5
12.27
2.453
2.01
0.121
Error
20
24.40
1.220
Total
29
67.47
There is significant differences between the 5 occasions, F=6.31, P=0.002.
(b) Use the Bonferroni procedure to make the post hoc test. In which week do we first see significant differences compared to baseline?
Comparisons for data
Bonferroni Pairwise Comparisons: time
Grouping Information Using the Bonferroni Method and 95% Confidence
time
N
Mean
Grouping
Baseline
6
3.50000
A
week2
6
1.50000
A
B
week4
6
1.00000
B
week6
6
0.83333
B
week8
6
0.83333
B
Means that do not share a letter are significantly different.
Week 2 is the first week where significant differences from baseline are evident.
Answer: Week 4 is the first week where significant differences from baseline are evident.
Week 6 is the first week where significant differences from baseline are evident.
Week 8 is the first week where significant differences from baseline are evident.
None of the weeks are significantly different from the baseline.
Source
DF
Adj SS
Adj MS
F-Value
P-Value
time
4
30.80
7.700
6.31
0.002
subject
5
12.27
2.453
2.01
0.121
Error
20
24.40
1.220
Total
29
67.47
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