According to a recent study, 1 out of 50,000 people will be diagnosed with cysti

Question

According to a recent study, 1 out of 50,000 people will be diagnosed with cystic fibrosis. Cystic fibrosis can be caused by a mutant form of the CFTR gene (dominant gene symbol is F and mutant is f).

A.) Using the rate of incidence above, what is the frequency of carriers of the cystic fibrosis allele for CFTR in the US?

B.) In a clinical study, 400 people from the population mentioned in (a.) were genotyped for BRCA1 gene. Listed below are the results. Are these results in Hardy-Weinberg equilibrium? Use statistics to show whether or not they are.

genotype # of women

                  BB                                    390                   

                  Bb                                        10

                  bb                                          0

Explanation / Answer

A.) Hardy-Weinberg equation (p

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