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Dude, a chromosomally normal male, is married to Dudette, who is also chromosoma

ID: 34030 • Letter: D

Question

Dude, a chromosomally normal male, is married to Dudette, who is also chromosomally normal. Their son, Dudester, has Klinefelter syndrome.

Please indicate whether each of the following events could have produced the Dudester.

In each case, assume that ALL other phases of cell division occur normally. For example, if the non-disjunction occurs in meiosis I in Dude, this implies that meiosis II in Dude is normal, and so is meiosis I and II in Dudette.

a.         Non-disjunction in meiosis I in Dudette

b.         Non-disjunction in meiosis II in Dudette

c.         Non-disjunction in meiosis I in Dude

d.         Non-disjunction in meiosis II in Dude

Explanation / Answer

Ans.

KlineFelter's Syndrome = XXY chromosomes condition

b.         Non-disjunction in meiosis II in Dudette
(Due to Birth of a cell with karyotype XXY due to a Non-Disjunction event of one X chromosome from a Y chromosome during Meiosis I in the Male)

c.         Non-disjunction in meiosis I in Dude
(Due to Birth of a cell with karyotype XXY due to a Non-Disjunction event of one X chromosome during Meiosis II in the Female)

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