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4. Using the product rule, what is the probability that parents heterozygous for

ID: 34094 • Letter: 4

Question

4. Using the product rule, what is the probability that parents heterozygous for two traits (AaBb) produce offspring heterozygous for the same two traits (aaBb? (Show work) 5. For two traitsCand D with two alleles each, what are the genotypes of the gametes that each heterozygote would produce? 6. Below is a pedigree showing the inheritance pattern for a rare type of migraine disorders. All affected individuals are shaded; normal individuals are not shaded. Use you knowledge regarding modes ofinheritance to answer the questions. HTO male female a. What is the mode of inheritance or transmission for the migraine disorder? b. Why does individual II-2 have the migraine disorder and what is his genotype? c. What is the probability (chance)that individual III-1 will have a child suffering migraines?

Explanation / Answer

4) Parent's genotype AaBb. SO, the gametes of each parent would look like this AB, Ab, aB, ab & AB, Ab, aB, ab

when they are crossed the resultant offsprings' genotype would be as followed

AABB AABb AaBB AaBb

AABb AAbb AaBb Aabb

AaBB AaBb aaBb aaBb

AaBb Aabb aabb aabb

So, 2 out of 16 would be of aaBb genotype.

5) As there are two alleles for each gene and parent is heterozygous the genotype of parent would be CcDd.

So, the gametes produced by such heterzygous parent would look like this

1) CD 2) Cd 3) cD 4) cd

6) a) mode of inheritance is X-linked dominant

b) Heterozygous Mm (M dominant m recessive)

c) 50 % chances are there to have a child suffereing from migrane

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