Chi Squared Question 2 Medical researchers reported on the effectiveness of the

Question

Chi Squared Question 2

Medical researchers reported on the effectiveness of the drug Infliximab in treating Crohn's disease. 335 patients who had responded positively to the drug in an earlier trial were randomly assigned to three groups. 110 people in Group I received injections of a placebo. 113 people in Group II received injections of 5 mg of Infliximab. 112 people in Group III received injections of 10 mg of Infliximab. After 30 weeks, 23 of the Group I patients, 44 of the Group II, and 50 of the Group III patients were in remission. Do these data indicate that continued treatment with Infliximab is of value to Crohn's disease patients who responded positively to an initial treatment with the drug?

Explanation / Answer

The test hypothesis:

Null hypothesis: continued treatment with Infliximab is of value to Crohn's disease patients who do not respond positively to an initial treatment with the drug

Alternative hypothesis: continued treatment with Infliximab is of value to Crohn's disease patients who responded positively to an initial treatment with the drug

Col 1   Col 2   Col 3   Total   Row 1 Observed   110 113 112 335 Expected   98.57 116.36 120.07 335.00 (O - E)

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