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The chemical 2.4 dinitrophenol (DNP) is used in the manufacturing of dyes, and a

ID: 34383 • Letter: T

Question

The chemical 2.4 dinitrophenol (DNP) is used in the manufacturing of dyes, and as a photographic developer. Products containing DNP are toxic because DNP acts as a proton channel, preventing the formation of a proton gradient in the mitochondria. In a cell exposed to DNP, how many ATP molecules would be generated per molecule of glucose?

a)the same number of ATPs as generated during fermintation, since there is no chemiosmosis

b)More ATPs than during fermintation , since the cell still preforms the Kreb cycle

c)same number of ATP as produces during regular aerobic respiration, since the cell still preforms the electron transport chain

Explanation / Answer

Chemiosmosis gradient can no longer be created in the mitochondria due to uncoupling of electron transport from ATP synthesis. So, in the presence of 2,4 DNP the same number of ATPs are generated during fermentation.

Hence, the correct option is (a) the same number of ATPs as generated during fermentation, since there is no chemiosmosis.

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