Of 2,872 persons who had received radiation treatment in childhood because of an
ID: 3439110 • Letter: O
Question
Of 2,872 persons who had received radiation treatment in childhood because of an enlarged thymus, cancer of the thyroid developed in 24 and a benign thyroid tumor developed in 52. A comparison group consisted of 5,055 children who had received no such treatment (brothers and sisters of the children who had received radiation treatment). During the follow-up period, none of the comparison group developed thyroid cancer, but benign thyroid tumors developed in 6. Calculate the relative risk for benign thyroid tumors: _____
Please show calculations. Thanks!
Explanation / Answer
Of 2,872 persons who had received radiation treatment in childhood because of an enlarged thymus, cancer of the thyroid developed in 24 and a benign thyroid tumor developed in 52. A comparison group consisted of 5,055 children who had received no such treatment (brothers and sisters of the children who had received radiation treatment). During the follow-up period, none of the comparison group developed thyroid cancer, but benign thyroid tumors developed in 6. Calculate the relative risk for benign thyroid tumors: _____
Please show calculations
The relative risk or risk ratio is given by
Total
benign thyroid tumor
No tumour
Incidence
Treatment
a
b
a+b
a/(a+b)
control
c
d
c+d
c/(c+d)
Relative risk=
(a/(a+b)) / (c/(c+d))
Total
benign thyroid tumor
No tumor
Incidence
Treatment
52
2,820
2,872
52/2872=0.0181
control
6
5,049
5,055
6/5055=0.0012
Relative Risk = 0.0181/0.0012=15.08
Total
benign thyroid tumor
No tumour
Incidence
Treatment
a
b
a+b
a/(a+b)
control
c
d
c+d
c/(c+d)
Relative risk=
(a/(a+b)) / (c/(c+d))
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