What research result convinced Goldman/Hodgkin/Katz that animal cells have a mem

Question

What research result convinced Goldman/Hodgkin/Katz that animal cells have a membrane potential that is at steady state (not a thermodynamic equilibrium) and that the concentration (and permeability) of all ions, to which the membrane is permeable, must be taken into account when determining the resting membrane potential?

A) blocking the sodium/potassium pump leads to a more negative membrane potential than normal

B) elevating extracellular sodium concentrations causes a membrane potential more positive than normal

C) at very low extracellular potassium concentrations, the membrane potential is more positive than predicted by the Nernst equation

Explanation / Answer

The ans is B.

Increase extracellular sodium causes vm to become more positive as the membrane gets depolarised.

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