Arrange the steps in their proper order to demonstrate your knowledge of the seq

Question

Arrange the steps in their proper order to demonstrate your knowledge of the sequence of events during an action potential. Local membrane is brought to threshold voltage by a depolarizing stimulus. +30 Steady resting membrane potential is near EK, PK> PNa due to leak K* channels. 6 Closure of voltage-gated K' channels returns the membrane potential to its resting value Threshold potential Outward current through open voltage-gated K channels repolarizes the membrane back to a negative potential -70 O Resting mombrane o Pers stent current trough slowy closing voitage-gated Kchannels hyperpolarizes membrane toward EK. Na' channels return from inactivated state to closed state 1 Current through opening votage-gated Na' channels rapidly depo arizes the membrane, causing more Na" channels to open. Inactivation of Nat channels and delayed opening of voltage- gated K+ channels halt membrane depolarization. 4 6 Reset

Explanation / Answer

Steady resting membrane potential is near Ek Local membrane is brought to threshold voltage by a depolarising stimulus Current through opening voltage gated sodium channels rapudly depolarising the membrane causing more sodium channels to open Inactivation of sodium channels and delayed opening of potassium channels halt membrane depolarisation Outward current through open voltage gated potassium channels repolarises the membrane back to negative potential Persistent current through slowly closing potassium channels hyperpolarises the membrane Closure of voltage gated potassium channels returns the membrane potential to its resting value

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