Let\'s do some true/false questions. That\'s pretty much it; you determine if th

Question

Let's do some true/false questions. That's pretty much it; you determine if the statement is true or false regarding sensory physiology in unmanipulated/standard circumstances. (/4 point each) all somatosensory receptors continually fire while the stimulus is applied increasing the intensity of a stimulus always increases the amplitude of the receptor potential neural connectivity within the somatosensory cortex can change with experience only neurons can detect changes in the external environment Your skin has been exposed to a noxious stimulus on the right arm. Using this pool below, your job is to tell the story of now that information makes its way to the somatoasensory cortex for processing. Not all steps will be used, not all steps are included. (/4 point each) a) 1" order neuron axon ascends dorsolateral column b) 2"° order neuron axon ascends anterolateral column c) 2"d order neuron axon crosses over in the brainstem d) 2hd order neuron axon crosses over in the spinal cord e) 2hd order neuron dendrite crosses over in the spinal cord f) 3'd order neuron innervates the left somatosensory cortex g) 3° order neurons innervates the right somatosensory cortex h) Merkel cell stimulated in the right arm i) nociceptor stimulated in the right arm j) Pacinian corpuscle stimulated in the right arm Event #1 Event #2 Event #3 Event #4 You and your team of researchers at BigPharma are working hard to develop a new medication that would help reduce chronic pain. However, you don't want to run into any copyright infringement issues with other analgesics, so you cannot supplement the endogenous opioids with exogenous opiates. So... out of the options below, which would BEST accomplish your goal with minimal unintended side effects? (/2 point) a) decrease responsiveness of second order neurons b) decrease voltage-gated sodium ion channel availability c) increase activity of opioid reuptake proteins d) increase expression of opioid receptors

Explanation / Answer

1. 1. True. If the stimulus is strong enough to ellicit a response then there definately will be firing of impulses. However if it is strongly stimulated, then the firing rate eventually decreases - phenomenon known as adaptation.

1.2 . True.

1.3.True.

1.4 False: only sensory neurons can detect changes in external environment. In turn they relay this information to the other neurons.

2. event 1: j: nocireceptors stimulated,

2.event 2: The first order neuron whose cell body is located in dorsal root ganglion will transmit the signal to dorsal horn of spinal cord via the anterolateral system (a).

2. event 3: d and b.

2. event 4 L (f)

3. (d)

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