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Gas transport regulation Place each of the following conditions in the proper ca

ID: 3475443 • Letter: G

Question

Gas transport regulation Place each of the following conditions in the proper category to predict whether the delivery of oxygen would be increased or decreased in normal sea-level conditions. Tissue PO2 of 60 mmHg Decreased temperature Increased hematocrit Carbon monoxide binding to heme Tissue PCO2 of 43 mmHg Decreased blood pH Alveolar PO2 o 86 mmHg Iron-deficiency anemia Right shift in the oxygen-hemoglobin dissociation curve 75% saturation of Hb leaving the alveolus Increased Q delivery to tissues Decreased Q delivery to tissues

Explanation / Answer

If the tissue partial pressure becomes 60 mm of Hg, then the oxygen suppy to the tissues increases.

Decreased temperature increases oxygen affinity for hemoglobin, this decreases the release of oxygen to tissues.

Increased hematocrit means low availability of oxygen, that means oxygen has more affinity for hemoglobin.

Carbon-monoxide has more affinity for hemoglobin compare to oxygen. Presence of carbon-monoxide decreases the affinity of oxygen and thus makes oxygen less available to tissues. This leads to hypoxia.

Decreased pH of blood lowers the affinity of oxygen for hemoglobin. This makes increase availability of oxygen to tissues.

Iron deficiency leads to inability of red blood cell formation. Inability of red blood cell formation leads to less binding to oxygen to red blood cells. This makes less available oxygen to tissues.

Right shift in the oxygen dissociation curve causes lower affinity of oxygen to hemoglobin, thus more oxygen diffuse towards the tissues.

75% saturation of hemoglobin with oxygen in the alveoli will leads to diffusin of oxygen to different parts or tissues.