3. The normal concentration for intra- and extracellular potassium in a neuron [

Question

3. The normal concentration for intra- and extracellular potassium in a neuron [K+] in = 140 mM and [K+]out = 4 mM. Due to an electrolyte imbalance, a pa has the following intra- and extracellular potassium levels: [K+] in 140 mM a [K+] out = 10 mM. Using the Nernst Equation, you calculate the new equilibri potential for potassium in this diseased patient and find it to be -70 mV. W llit easier or more difficult to generate an action potential in the diseased neu s a compared to normal? Why? TOSHIBA

Explanation / Answer

At rest, the K ions are more inside and Na ions are more outside. the membrane potential is due to the leakage of the K ions outside the cells. As the action potential reaches, the Na+ rushes inside and K+ outside which reverses the polarity. If already the K+ is more outside it will be easier to generate an action potential.

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