A researcher has created a biodegradable polymeric implant material that degrade

Question

A researcher has created a biodegradable polymeric implant material that degrades through a surface erosion mechanism. The material is intended to serve as a tissue engineering scaffold, in which long-term cell adhesion to the material is important. Initial studies have found that cells will not adhere to the surface of the material. The researcher is considering covalent attachment of a peptide sequence known to improve cell attachment to the surface of this material. The researcher asks if you support the idea? Will you support the idea? Why or why not?

Would bulk modification with the peptide sequence be a more or less appropriate method of modification for the intended result?

Explanation / Answer

Is there is an improvement in the send attachment to the surface of this material due to the polypeptide chain I would favour the decision as it result in a long time cell adhesion .

I would favour the idea is good as the polypeptide chain can bind to the cells and do the material which will provide the surface attachment. And can serve the function of device as we should be needed.

Bike modification of the peptide is less appropriate because as it is a protein protein can reach to the allergic reaction in the human body that it is an implant . Allergic rate with the higher protein content is generally high as the mostly antigen are made up of proteins and mostly human body identify their own receptors having a foreign particle can lead to the allergic reactions and graft rejection of the device can be the most severe form.

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