8. Number the folliowing statements in their proper sequence to describe the con
ID: 3477386 • Letter: 8
Question
8. Number the folliowing statements in their proper sequence to describe the contraction mechanism in a skeletal muscle celI. The Erst step has already been idenaified as number 1 LI. Acetylcholine is released into the neuromuscular junction by the axonal tenminal. 2· The action potential, camed deep into the cea, causes the sarcoplasmic reticulum to release caleiuen lons 3. The muscle cell relaxes and lengthens. 4 Acetylcholine diffuses across the neuromuscular junction and bincls to receptors on the sarcolemma. 5. The calcium ion concentration at the myofilaments increases: the myofilaments slide past one anoxher, and the cell shortens 6. Depolarization occurs, and the action potential is generated 7. As calctum is actively reabsorbed into the sarcoplasmic reticulum, its concentration at the myofilaments decreases 9. The following incomplete statements refer to a muscle cell in the resting, or polarized, state just before stimulation. Complete each statement by choosing the correct response from the key choices and entering the appropriate letter in the answer blanks. Key Choices A. Na* diffuses out of the cell B. K' diffuses out of the cell G. Relative ionic concentrations on the two sides of the membrane during rest C. Na" diffuses into the cell D. K' diffuses into the cell F. Inside the cell H. Electrical conditions I. Activation of the sodium-potassium pump, which moves J. Activation of the sodium-potassium pump, which moves K" into the cell and Na out of the cell Nat into the cell and K' out of the cell Outside the cell 1. There is a greater concentration of Na' (D and there is a 2. ered, the permeability of the membrane is changed, and 3. as soon as the depolarization wave begins, a repolarization 4. Repolarization restores the _(5) of the resting cell 5. 6. greater concentration of K2)When the stimulus is deliv- 3 initiating the depolarization of the membrane. Almost wave follows it across the membrane. This occurs as (0 membrane. The (6is (are) reestablished by 7 7.Explanation / Answer
8)1(1)Accetylecholine is released into the neuromuscular junction by the axonal terminal.
2(4)Accetylecholine diffuses across the neuro muscular junction and binds to receptors on the sarcolemma.
3(6)Depolarisation occurs and the action potential is generated.
4(2)The action potential carried deep into the cell causes the sarcoplasmic reticulum to release calcium ions,
5(5)The calcium ion concentration at the myofilament increases ;myofilament slide past one another and the cell shortens.
6(7) As calcium is actively reabsorbed into the sarcoplasmic reticulum ,its concentration at myofilament decreases.
7(3) The muscle cell relaxes and lengthens.
9) 1.F Outside the cell
2.E Inside the cell
3.C Na diffuses into the cell
4.B Pottasium diffuses out of the cell
5.H Electrical conditions
6.G relative ionic concentration on the two sides of the membrane during rest
7.I Activation of Na -K pump,which moves K in and Na out
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