MAKE THE CONNECTION Nutritional deficiencies interfere with cell metabolism and

Question

MAKE THE CONNECTION Nutritional deficiencies interfere with cell metabolism and tissue structure. Look up rickets in your textbook or other resource and describe how rickets affects the extracellular matrix of bone and describe how this change in extracellular matrix causes the symptoms of rickets. 1. Sphincters are circular muscles present in certain area of the body. Defecation and urination are controlled by a pair of sphincters-external and internal. 2. Which type of muscle tissue makes up these sphincters? Briefly explain how sphincters control these function in infants when they go from involuntary to voluntary control Tendons and ligaments have limited blood supply. Explain if and how it affects the repair process in case they get damaged. 3. Read about Marfan syndrome. Describe the tissue it involves: 4. Which organs/systems does it affect? What are the signs and symptoms?

Explanation / Answer

The extracellular matrix of the bone tissue is composed of one-third of organic and two-thirds of inorganic matter. The inorganic matter contains 85% of hydroxyapatite. It is a crystallized calcium phosphate salt. [Ca10(PO4)6(OH)2]. About 10% of calcium carbonates (CaCO3) and small amounts of magnesium, sodium, potassium, fluoride, sulfate, carbonate and hydroxide ions. Vitamin D is necessary for absorption of calcium through dietary sources. Deficiency of vitamin D results in poor calcium absorption and poor composition of extracellular matrix of bone. This may result in a condition called Rickets. Without proper extracellular matrix composition, the bones are not strong enough to bear the weight of the body. The bones become soft and porous and break easily. The symptoms of rickets include soft bones, bone pain, costochondral swelling, slow physical growth, bowed legs, knock knees and widening wrists.

Related Questions

Navigate

• Browse (All)
• Browse M
• Subjects

---

---

Integrity-first tutoring: explanations and feedback only — we do not complete graded work. Learn more.