Search 4:08 PM worksheet_membrane_potential.docx Worksheet: Understanding Membra

Question

Search 4:08 PM worksheet_membrane_potential.docx Worksheet: Understanding Membrane Potential Goals . Review fundamental information about cell membranes, ions, and electrochemical gradients. Understand and apply the Nernst and Goldman-Hodgkin Katz (GHK) equations. Determine whether an ion will go into or out of a cell if given the ion's concentration gradient and the cell's membrane potential. Nernst Calculator: culator html Electrochemical Driving Force Calculator: Fundamentally, the nervous system is an electrical system, i.e. messages are transmitted via the movement of charged particles (ions). The movement of a cation (such as Na") into a neuron has consequences very different from the movement of a cation out of that neuron. Since such ion movements underlie the functioning of the entire nervous system, it is vital to understand exactly why ions move in the directions that they move. 1. In Figure 1, place a large plus sign on the side of the membrane with the most positive charges and a large minus sign on the side of the membrane with the fewest positive charges. Model 2: A Polarized Membrane Open With Print

Explanation / Answer

1) plus outside and minus inside because even though both Na and K are positively charged, number of Na+ outside is larger than number of K+ inside.

2) hence from the above question outside will have a more positive potential as compared to inside.

3) Cl- is one of the anions that contribute to a cells membrane potential it is majorly localized inside making it more negative as compared to outside.

4) the membrane potential will pull K+ inside as opposite charges attract and so a positive charge will be attracted towards a negative potential which is inside.

5)contradictorily to the above question, the K+ ions will be pulled outside as solutes/ ions tend to move from a higher concentatration to a lower one. K+ concentration is high inside as compared to outside.

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