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7%201929.pdf av/pid-4099625-dt-content-rid-16822052 1/courses/2179 17642/Nephr G

ID: 3478558 • Letter: 7

Question

7%201929.pdf av/pid-4099625-dt-content-rid-16822052 1/courses/2179 17642/Nephr Glomerulus Capsule Net force Direction Parameter 40 mm Hg Into capsule 55 mm Hg 30 mm Hg 300 mOsmol 15 mm Hg Pressure Colloid OP Osmotic pressure Sum 1·The pressure in the glomerulus is 55 mm Hg. The back-pressure in the Bowman's capsule is 15 mm Hg. There, the net force, AP, is 40 mm Hg, driving the filtrate into the capsule 2. The glomerulus filters out all proteins and large, suspended particles. What is the colloid osmotic pressure in the Bowman's Colloid OP capsul? write your answer under "Capsule, What is ColloidOP? write your answer under-Net force. Colloid or. Under Direction, write whether the direction is into or out of the capsule the osmotic pressure of the blood is 300 mOsmol, what is the osmotic pressure in the capsule? Write your answer under "Capsule, Osmotic pressure S. What is the net force with which osmotic pressure drives uptake? Write it in the table as above. Indicate the direction 6. What is the total pressure and osmotic driving force moving fluid into the capsule? Proximal tubule worksheet The proximal tubule absorbs 2/3 of the NaCI and 2/3 of the water of the glomerular filtrate 1. The concentration of NaCI in the filtrate is 150 mM. What is the concentration of the mucosal solution as it exits the proximal tubule? 2. What is the approximate osmolarity of the filtrate. given that NaCI is the primary solute in the filtrate? 3. What is the approximate osmolarity of the mucosal solution as it exits the proximal tubule?

Explanation / Answer

1. Net force = Pressure Glomerulus - Pressure Capsule

=55 - 15 = 40

therefore net force is 40mmHg

2. It is given that the glomerulus filters out all proteins and large, suspended particles, therefore the absence of proteins in Bowman’s space (the lumen within Bowman’s capsule) results colloid OP in the capsule near zero.

3. Net OP would be the difference of glomerulus colloid OP and capsule colloid OP

Therefore, Net OP = 30-0 =30mmHg and its direction would be out of the capsule

4. As explained above the absence of proteins in Bowman’s space (the lumen within Bowman’s capsule) results in an osmotic pressure near zero.

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