People Window Help ome File Edit View History On a mac /W15 MS: Muscle metabolis
ID: 3479304 • Letter: P
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People Window Help ome File Edit View History On a mac /W15 MS: Muscle metabolis Grow to ezto.mheducation.com/hm.tpx Place a single word into each sentence to make it correct, and then place each sentence into a logical paragraph order tetanus When the frequency is progressively higher, the muscle does not have time to tension relax With moderately frequent stimulation, muscle relaxes fully between contractions, but successive twitches are stronger, a phenomenon known as twitch atency A quick cycle of contraction and relaxation of the muscle is called a The muscle will eventually fatigue and the muscle decline. will then threshold At an even higher frequency, the muscle exhibits a state of continual contraction, called treppe ResetExplanation / Answer
when the frequency is progressively higher the muscle does not have time to RELAX
* for a muscle to relax Ca2+ has to be pumped back from cytosol to sarcoplasmic reticulum. This can NOT occur fully when frequency of action potentials are high.
with moderately frequent stimulations muscle relaxes fully between the contractions, but successive twitches are stronger, a phenomenon known as TREPPE
* treppe or staircase phenomenon occurs as with moderate frequent stimulus application at repeated intervals will increase the cytosolic concentration Calcium ions, with each subsequent stimulation more Ca will lead to increased Ca-Troponin binding--> tropomysosin sliding--> binding of mysoin head on actin--> actin - myosin complex formation-->power stroke--> shortening-->increased amplitude of subsequent contractions(looking like a staircase, hence this name)
A quick cycle of contraction and relaxation of muscle is known as TWITCH
* Twitch is very fine and quick contraction and relaxation of muscles. sometimes they are visible, at other times they are detected on electromyography. Spontaneous depolarization of Lower Motor Neurones causes Twitch.
At an even higher frequency, the muscle exhibits the state of continual contraction, called TETANUS
* Tetanus is caused by the toxins of clostridium tetani, a bacteria.
the toxin is taken up by central nervous system where it can be released into synaptc clefts. tetanus toxin blocks inhibitory neurotransmitters(GABA,GLYCINE) and thereby results in development of hyperactive motor signals.
Heart muscles cannot be teatnized because of its long refractory period of 200 milliseconds
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